Critical Facts About Waterborne Diseases In The United States and Abroad, by John Hawthorne

If you live in a developed country, and I assume many of you are if you’re reading this, waterborne diseases probably aren’t something you typically worry about. But did you know that poor water sanitation and a lack of safe drinking water take a greater human toll than war, terrorism and weapons of mass destruction combined?

Even in America, pumps, pipes and purification facilities could all fail, leaving you susceptible to waterborne diseases.

So what exactly are waterborne diseases? How many people are actually affected by them? How do we keep our water clean and safe? How many people are dying from these diseases, and what can we do to prevent that from happening? We’ll answer all of those questions here.

How Much Drinkable Water Is There?

First things first. Before we can understand why waterborne diseases are so prevalent, we need to have a clear understanding of how much drinkable water is actually available.

While nearly 70 percent of the world is covered in water, only 2.5 percent of it is drinkable. And of that, only 1 percent of it is easily accessible, with the rest trapped in glaciers and snowfields.

Since most of the Earth’s fresh water is frozen at the North and South poles, that leaves the rest of the fresh water in surface water and groundwater. Surface water is found in the Earth’s lakes, rivers, and streams. Groundwater is just surface water that has made its way into the soil.

You might be wondering if we will ever run out of fresh water. Our population is rapidly increasing, and most of our uses for fresh water are increasing right along with it. So, will we always have enough fresh water to go around?  We will.

The Earth is very efficient when it comes to recycling its water.  Every drop of water continue to read the article

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Beyond the Information Age: What Next?

The world has experienced a series of Revolutions. The 21st century is highly characterised with information explosion like never before in human history. Today, with just a click on a mouse, interested individual can access scores of information on virtually any issue of concern in life. Gone are the days when few ‘elites’ reigns in knowledge and intellectual prowess over the majority. Nations that recognizes the importance of information-empowerment to her citizenry have left no stone unturned in entrenching it in their constitution as a fundamental/civic right of the governed. Decades ago, nations that appeared as world ‘giants’ are today facing stiff competition from emerging world powers owing to information technology.

It spread so fast as with a scourge on rampage, covering lands and territories, infecting inhabitants of high-tech nations in the West to village dwellers of developing communities in Africa with its ‘sting’ of relevance. In the years preceding the 21st century, when an issue of global or national interest occurs and those in the corridors of powers decides to conceal such from the knowledge of the people, they succeeded in some cases. There were high secrets in high places. Today, the converse is the case. With the advent of the internet, information dissemination and closing of knowledge gap has been made much easier. Such accounts for what makes the headliners in most local and international dailies as the corrupt hidden ‘mess’ of unscrupulous elements are brought to bear and appropriate penalty applied. Those professionally vested with the responsibility of acting as ‘bridgers’ between the government and the governed are alive to their responsilities with the adoption and implementation of the freedom of information law. What is more, the various component regions of the world are inter-dependent on one another in a global village. No doubt, access to information in an unprecedented scale is a gift to our generation. Continue reading “Beyond the Information Age: What Next?”

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A Step Closer to a Screening Test for Stuttering

A screening test for children starting school that could accurately detect early signs of a persistent stutter is a step closer, experts say.

The Wellcome Trust team says a specific speech test accurately predicts whose stutter will persist into their teens.

About one in 20 develops a stutter before age five – but just one in 100 stutter as a teen and identifying these children has so far been difficult.

Campaigners said it was key for children to be diagnosed early.

Stuttering tends to start at about three years old. Four out of five will recover without intervention, often within a couple of years.

But for one in five, their stutter will persist and early therapy can be of significant benefit. Continue reading “A Step Closer to a Screening Test for Stuttering”

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Goal-line technology Approved International Football Association Board

Goal-line technology has been given the go-ahead by the International Football Association Board (IFAB) following a vote at Fifa headquarters in Zurich.

Two systems – Hawk-Eye and GoalRef – have been approved after passing a series of scientific tests.

They will first be used at December’s Club World Cup – which features Chelsea – and, if successful, at the 2013 Confederations Cup and 2014 World Cup.

It could even be introduced during the 2012-13 Premier League campaign.

In a statement following the announcement, the Premier League said it had been a “long term advocate of goal-line technology”.

“We welcome today’s decision by IFAB and will engage in discussions with both Hawkeye and GoalRef in the near future with a view to introducing goal-line technology as soon as is practically possible.”

FA general secretary Alex Horne said it was up to the Premier League to decide on a timescale for implementation.

“It may be December until the technology is absolutely finally approved and installed in stadia,” he said at a press conference in Zurich. “Priority is given to the Fifa Club World Cup in Japan.

“The Premier League need to talk to the two [technology providers] and the clubs. My understanding is that clubs are supportive and, in principle, as long as all clubs agree it could be introduced part-way through the season, it could be before the start of 2013-14 season, it could be part way through.

“It might be that it is possible to have it part way through the [2012-13] season. If all 20 clubs agree a switch-on weekend I don’t think anyone is disadvantaged[ad#GBAF-2-pix]

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Scientists Find More Than Ten Thousand Microbes in Humans

“When I get up from my chair, ten times more bacterial cells get up than human ones,” says Dr Bruce Birren.

He is one of the hundreds of US scientists involved in the world’s most extensive map of the microbes that live in and on us.

The Human Microbiome Project has catalogued the genetic identity of many bacteria, viruses and other organisms that live in intimate contact with us.

They are not germs that need eliminating but a fundamental part of what makes us human, researchers say.

“I might have a different organism on my tongue than you do on your tongue but collectively they bring the same genes to the party..”

Yet until recently, little was known about the identity of trillions of the microbes populating our bodies.

‘Beneficial bugs’

For centuries we could only investigate microbes that can survive in laboratories and study them in isolation – often one microbe at a time.

But with the advent of ever-improving techniques to sequence DNA, the Human Microbiome Project has been able to uncover microbes that have never been seen before and look at how they behave as communities.

Many of the results of the five-year project, launched by the National Institutes of Health, have been published in Nature and PLoS journals.

Over 200 healthy men and women from the US had microbe samples taken from various parts of their bodies.

And researchers were able to find over 10,000 different types of organisms as part of the healthy human microbiome.

Most of these microbes appeared to do no harm at all. In fact, there is growing evidence that these bugs help us in many ways.

Some help us get energy from food and others help us absorb nutrients such as vitamins.

‘Shared microbes?’

And we are learning about the role they play in shaping, rather than just attacking our immune systems, says Prof Barbara Methe of the J Craig Venter Institute, also involved in the project.

One of the key questions researchers asked was – is there a core set of microbes that all humans share?

Scientists actually found a diversity of microbes across different human beings and unique communities of microbes living at different body sites.

But what surprised some is that at specific parts of the body, many of the microbes shared similar jobs.

“I might have a different organism on my tongue than you do on your tongue but collectively they bring the same genes to the party – so they are able to perform some of the same functions, for example, breaking down sugars,” Dr Birren says.

This finding suggests a shift in thinking from a one-microbe model of disease, that essentially pins the blame for certain illnesses on one bug.

‘Bacterial phone-book’

Perhaps what matters in some diseases is not the particular type of bug, but that the function of this group of bugs has somehow gone awry, Dr Huttenhower says.

Researchers found that healthy volunteers carry low levels of microbes, classically been thought to cause disease.

For example, the bacteria Staphylococcus aureus, which can be involved the infection MRSA, was found in the noses of about 30 percent.

“We now have a phone-book of 100 of these bugs, which in the right environment, have the potential to go bad.

“We know where they live in healthy people and which organisms surround them too. So perhaps we can begin to understand what keeps them in check and where their reservoirs are,” Dr Huttenhower says.

And most microbes carry at least 100 times as many genes as we do.

These genes have just as much ability to influence our health and disease-risk as our own, says Dr Curtis Huttenhower, from the Harvard School of Public Health, another contributor to the project.

The ability to refer to this new genetic database and investigate microbiomes that fall outside its boundaries, will be the long-term importance of this project, he says.

‘Unknown land’

Dr Lita Proctor, programme director of the project says there is a growing understanding that we pick it up in the very early stages of life.

“The human genome is inherited but the human microbiome is acquired- that means it has a very important changeable, mutable property.

“This gives us something to work with in the clinic. If you can manipulate the microbiome you can keep a healthy microbiome healthy or re-balance an unhealthy one,” she says.

But who owns the microbiomes inhabiting our bodies? And what does this mean for the regulation of pro-biotics that can change them?, asks ethicist Prof Any McGuire of Baylor College of Medicine.

These are questions that will need to be ironed out as our knowledge of this area expands, she says.

But we only have half the story. We need to find out much more about how the microbiome talks to human cells says Prof David Relman of Stanford University.

“It is still an unknown land. Even though it is on home turf we are still discovering new life forms on it,” he says.

Human Microbiome Project reveals largest microbial map

By Smitha Mundasad BBC News

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Fight Against Malaria Compromised by Resistance Spread

Scientists have found new evidence that resistance to the front-line treatments for malaria is increasing.

They have confirmed that resistant strains of the malaria parasite on the border between Thailand and Burma, 500 miles (800km) away from previous sites.

Researchers say that the rise of resistance means the effort to eliminate malaria is “seriously compromised”.

The details have been published in The Lancet medical journal.

For many years now the most effective drugs against malaria have been derived from the Chinese plant, Artemisia annua. It is also known as sweet wormwood.

In 2009 researchers found that the most deadly species of malaria parasites, spread by mosquitoes, were becoming more resistant to these drugs in parts of western Cambodia.

This new data confirms that these Plasmodium falciparum parasites that are infecting patients more than 500 miles away on the border between Thailand and Burma are growing steadily more resistant.

The researchers from the Shoklo Malaria Research Unit measured the time it took the artemisinin drugs to clear parasites from the bloodstreams of more than 3,000 patients. Over the nine years between 2001 and 2010, they found that drugs became less effective and the number of patients showing resistance rose to 20%.

Prof Francois Nosten, who is part of the research team that has carried out the latest work, says the development is very serious.

“It would certainly compromise the idea of eliminating malaria that’s for sure and will probably translate into a resurgence of malaria in many places,” he said.

‘Untreatable malaria’

Another scientist involved with the study is Dr Standwell Nkhoma from the Texas Biomedical Research Institute.

“Spread of drug-resistant malaria parasites within South East Asia and overspill into sub-Saharan Africa, where most malaria deaths occur, would be a public health disaster resulting in millions of deaths.”

The scientists cannot tell if the resistance has moved because mosquitoes carrying the resistant parasites have moved to the Burmese border or if it has arisen spontaneously among the population there. Either way the researchers involved say it raises the spectre of untreatable malaria.

“Either the resistance has moved and it will continue to move and will eventually reach Africa. Or if it has emerged, now that artemisinin is the standard therapy worldwide then it means it could emerge anywhere,” Prof Nosten told the BBC.

“If we were to lose artemisinin then we don’t have any new drugs in the pipeline to replace them. We could be going back 15 years to where cases were very difficult to treat because of the lack of an efficacious drug.”

Artemisinin is rarely used on its own, usually being combined with older drugs to help fight the rise of resistance. These artemisinin based combination therapies are now recommended by the World Health Organization as the first-line treatment and have contributed substantially to the recent decline in malaria cases in many regions.

Prof Nosten says the current spread of resistance could be similar to what happened in the 1970s with chloroquine, a drug that was once a front-line treatment against the disease.

“When chloroquine resistance reached Africa in the middle of the 1970s it translated into a large increase in the number of cases and the number of children who died increased dramatically.”

In a separate paper published in the journal Science researchers have identified a region of the malaria parasite genome that is linked to resistance to artemisinin.

Dr Tim Anderson, from Texas Biomed who led this study, says that while mapping the geographical spread of resistance can be challenging it may be hugely beneficial.

“If we can identify the genetic determinants of artemisinin resistance we should be able to confirm potential cases of resistance more rapidly. This could be critically important for limiting the further spread of resistance.”

According to the World Malaria Report 2011 malaria was responsible for killing an estimated 655,000 people in 2010 – more than one every minute. A majority of these were young children and pregnant women.

The BBC  Science Reporter

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Climate Change: South Africa Could See Enormous Change

JOHANNESBURG — Imagine the savannas of South Africa’s flagship Kruger Park so choked with brush, viewing what game is left is nearly impossible. The Cape of Good Hope without penguins. The Karoo desert’s seasonal symphony of wildflowers silenced.

Climate change could mean unthinkable loss for South Africa, which hosts talks on global warming that will bring government negotiators, scientists and lobbyists from around the world to the coastal city of Durban next week.

Guy Midgley, the top climate change researcher at the South African National Biodiversity Institute, said evidence gleaned from decades of recording weather data, observing flora and fauna and conducting experiments makes it possible for scientists to “weave a tapestry of change.”

Change is, of course, part of the natural world. But the implications of so much change happening at once pose enormous questions, said Midgley, who has contributed to the authoritative reports of the United Nations’ Nobel Prize-winning Intergovernmental Panel on Climate Change.

In the Karoo, for example, where plants found nowhere else in the world have adapted to long, dry summers and winter rainfall, the weather pattern is changing.

Scientists have noted large die-offs linked to the stress of drought among one iconic Karoo denizen, the flowering quiver tree, a giant aloe that often is the only large plant visible across large stretches of desert. Quiver trees attract tourists, and insects, birds and mammals eat their flowers.

“Any change in climate is going to affect the flowers,” said Wendy Foden, a southern African plant specialist with the International Union for Conservation of Nature.

Barend Erasmus, an ecologist at Johannesburg’s University of the Witwatersrand, worked on some of the first efforts to model how Africa might be affected by climate change. He led a 2001 study that raised the possibility that up to two-thirds of the species studied might disappear from Kruger National Park.

Research done since has made Erasmus less fearful for Kruger’s animal population. But he predicts profound effects should a changing climate encourage the growth of thick shrubs, squeezing out zebra, antelope and cheetah.

Already, he said, zebra and wildebeest numbers are declining in Kruger as their grazing areas disappear. The question is how much of the cause is due to high concentrations of carbon dioxide, and how much depends on other factors, including man’s encroachment.

Offshore, penguin expert Rob Crawford has looked at changes in the breeding grounds of African penguins and other seabirds, noting South Africa’s northernmost penguin colony went extinct in 2006. Crawford and his colleagues wrote in a 2008 paper that the movements “suggest the influence of environmental change, perhaps forced by climate.”

The African penguin, also known as the jackass penguin because of its braying call, is found only in southern Africa. A colony near Cape Town has long been a tourist draw.

One penguin parent stays behind to nest and care for offspring, while the other seeks food for the family. If the hunting partner is away too long, the nesting parent has to abandon the chick – or starve. Species like sardines, on which the penguins depend, have been displaced.

“If they don’t have sardines, they can’t feed their chicks,” Erasmus said. “And eventually the colonies just disappear.”

The numbers of African penguins have plummeted from up to 4 million in the early 1900s to 60,000 in 2010, according to the Southern African Foundation for the Conservation of Coastal Birds. Researchers blame humans, who collected penguin eggs for food until the 1960s. More recently, a new threat came with oil spills and commercial fishing’s competition for anchovies and sardines.

Erasmus said more research needs to be done, including studies on how plants and animals react to extreme conditions.

A colleague at his university, Duncan Mitchell, has taken up the challenge by tracking and studying antelope living in one of the hottest and driest corners of South Africa.

“We’re hoping to find that they have a capacity to deal with water shortage that they’re not having to use at the moment,” Mitchell said.

“Climate change is going to happen,” Mitchell said, adding it’s already too late to influence temperatures and water levels over the next four decades. “What needs to be researched is coping with unmitigated climate change.”

Coping might involve moving vulnerable animals to cooler habitats – or ensuring they’re not so hemmed in by human settlements that they cannot migrate on their own. Park rangers may have to work harder to remove trees to protect savannas. The South African government has called for expanding gene banks to conserve vulnerable species.

Sarshen Marais, a policy expert for Conservation International, says the work her organization is doing to eradicate foreign plants and help farmers better manage their land and water has gained importance.

Climate change experts fear water could become even scarcer in the future, but farmers can take steps that will help cash crops as well as wildlife. Conservation International has encouraged local communities to cut down thirsty foreign plants and sell the debris for fuel, allowing impoverished South Africans to earn while they save native species that are losing in the competition for water.

Researcher Erasmus acknowledges that in a developing country like South Africa, it can be hard to prioritize the plight of plants and animals. But he said an economic argument can be made, including the impact on people living in savannas who supplement their diets with small birds, other animals and wild greens, and who make money selling native fruits.

Tourism also is a consideration.

“Kruger is a cash cow for the whole of SANParks,” he said, referring to the national parks department.

Foden, the plant specialist, said that when she thinks of her native South Africa, she thinks of wide spaces filled with a stunning diversity of plants and animals.

“If we were to lose that,” she said, “we would lose so much of our identity.”

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Aids-related Deaths ‘Down 21% From Peak’, says UNAids

Aids-related deaths are at the lowest level since their 2005 peak, down 21%, figures from UNAids suggest.

Globally, the number of new HIV infections in 2010 was 21% down on that peak, seen in 1997, according to UNAids 2011 report.

The organisation says both falls have been fuelled by a major expansion in access to treatment.

Its executive director, Michel Sidibe, said: “We are on the verge of a significant breakthrough.”

He added: “Even in a very difficult financial crisis, countries are delivering results in the Aids response.

“We have seen a massive scale up in access to HIV treatment which has had a dramatic effect on the lives of people everywhere.”

‘End in sight?’

This latest analysis says the number of people living with HIV has reached a record 34 million.

Sub-Saharan Africa has seen the most dramatic improvement, with a 20% rise in people undergoing treatment between 2009 and 2010.

About half of those eligible for treatment are now receiving it.

UNAids estimates 700,000 deaths were averted last year because of better access to treatment.

That has also helped cut new HIV infections, as people undergoing care are less likely to infect others.

In 2010 there were an estimated 2.7m new HIV infections, down from 3.2m in 1997, and 1.8m people died from Aids-related illnesses, down from 2.2m in 2005.

The figures continue the downward trend reported in previous UNAids reports.

The UN agency said: “The number of new HIV infections is 30-50% lower now than it would have been in the absence of universal access to treatment for eligible people living with HIV.”

Some countries have seen particularly striking improvements.

In Namibia, treatment access has reached 90% and condom use rose to 75%, resulting in a 60% drop in new infections by 2010.

UNAids says the full preventive impact of treatment is likely to be seen in the next five years, as more countries improve treatment.

Its report added that even if the Aids epidemic was not over: “The end may be in sight if countries invest smartly.”

‘Promising moment’

The charity Medecins Sans Frontieres urged governments to keep up their funding.

MSF’s Tido von Schoen-Angerer, said: “Never, in more than a decade of treating people living with HIV/Aids, have we been at such a promising moment to really turn this epidemic around.

“Governments in some of the hardest hit countries want to act on the science, seize this moment and reverse the Aids epidemic. But this means nothing if there’s no money to make it happen.”

The International HIV/Aids Alliance said: “We welcome the ongoing commitment of UNAids to changing behaviours, changing social norms and changing laws, alongside efforts to improve access to HIV treatment.

“For bigger and better impact though, we must not be complacent. There is still much more to do.”

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