Canadians Make Malaria Breakthrough

Mother and daughter sleep under mosquito net to prevent bites from the parasite carrying mosquito

Lana Haight, Postmedia News

SASKATOON — Scientists in Saskatoon have developed an inexpensive malaria treatment that will help the million people who die every year from the infection.

“This is the most important drug in the treatment of malaria today. The World Health Organization says it should be the first line of defence,” said Patrick Covello, a senior research officer at the National Research Council in Saskatoon.

Covello and his team figured out a way to produce a difficult-to-cultivate chemical needed to build effective malaria drugs.

The breakthrough was announced Friday at the National Research Council Plant Biotechnology Institute.

The best drugs available to fight malaria are made with artemisinin, a compound derived from the sweet wormwood plant found in parts of Asia and Africa. But cultivating and harvesting the plant and then extracting artemisinin is time-consuming and labour intensive, says Covello. And the supply of the natural compound is also dependent on weather and growing conditions.

In 2003, Covello began work to identify the genes in the wormwood plant that produce the protein that leads to artemisinin.

“We identified four genes in what we call the pathway to artemisinin in the plant,” he said in an interview.

Meanwhile, University of California at Berkley researchers found they could develop a precusor to artemisinin by introducing chemicals into yeast.

Covello contacted Amyris Technologies, a spinoff company from the Berkeley research group, to suggest it use the genes his group had identified in the wormwood plant. When two of the genes identified in Saskatoon were introduced to the yeast compound developed at Berkeley, the production of artemisinin doubled.

The Institute for OneWorld Health, the American-based organization that has led the project to develop the semi-synthetic artemisinin, and pharmaceutical company Sanofi-aventis jointly announced on Friday that the drug company is preparing to ramp up production using the genes identified in Saskatoon.

The Bill & Melinda Gates Foundation, which has already contributed $42.6 million toward the American research, is also supporting the production of the drug to ensure it will be available on a not-for-profit basis for the developing world.

“The idea is to provide the developing world with antimalarial drugs at the lowest possible cost and, in addition, to provide a very stable supply because this yeast-fermentation process is shorter term and more reliable than growing the plants themselves,” said Covello.

Covello understands that Sanofi-aventis will begin commercial-scale production in 2012.

The federal government has spent $869,000 over eight years to support the Saskatoon research.

“Our government is committed to improving the health of women and children in developing countries,” said Gary Goodyear, minister of state for science and technology, in a government news release.

“This new development in the production of a malaria treatment represents a major development in the fight against the disease. It will strengthen Canada’s position as a world leader in health research and provide a reliable and affordable solution.”

The Vancouver Sun
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Before Egypt and Libya, There was Ivory Coast

Libya (left), Ivory Coast (right)

Foreign Policy Hypocrisy of Our Generation

Over the past two months, the world has keenly being following the political events in Egypt and Libya. Television screen at homes, schools, workplaces and major airport had one item on the waiting list: when the Egyptian President Hosni Mubarak would make his next statement and what would be the response of the US President Barack Obama. Facebook and Twitter were and are still floating in traffic like hell. Journalists who were hitherto unknown are now household names because of their coverage of the North African revolution. Some journalists were happily beaten up just to cover the news and they still enjoy it. Some risked their very lives just get their stories out.

The situation in Egypt and Libya ‘needed’ to be covered; the two countries play strategic roles in the US and European countries’ foreign policies. Both countries hold sweet big oil in their bosoms and the West likes that milk. Egypt does not directly make a momentous contribution to the global oil supply but it hosts the Suez Canal which is a major boulevard for oil transport to the US and other western countries. It’s also an excellent vacationer destination for the most westerners who periodically need to take a break. Libya, on the other hand, is a big player in the global oil market. The country is a swollen with pride for being a member of the OPEC and is the world’s 17th largest oil producer, the third-largest producer in Africa and holds the continent’s largest crude oil treasury. About 85% of Libya’s oil is exported to Europe. The penalty of the crisis in the two countries need not be recounted. In the US, regular fuel is now nearly $4 per gallon. Doesn’t this explain why twitter, Facebook, CNN, MSNBC and BBC are on Libya 24/7?

Another country, on the same continent, which is on the threshold of civil war and perhaps genocide, is the Ivory Coast. In fact the situation in the Ivory Coast started several months before there was a single protest in Tunisia, Egypt and Libya. How much on Ivory Coast can we find on Facebook feeds? How much is atwitter? When was the last time you heard somebody call the US too weak for not calling on Laurent Gbagbo to hand over to the constitutionally elected president? In fact, how many even know who that man is?

Two weeks ago, six women were killed in the Ivory Coast by forces supporting the incumbent tyrant Laurent Gbagbo, while on a peaceful demonstration. How much coverage did the western media bestow to that story? Actually, have you heard it? How many American reporters have questioned the President of the US or his Press Secretary where US stands on the Ivory Coast crisis?

Well, the truth is unlike Egypt and Libya, the Ivory Coast has not yet had a dream of producing oil for their local consumption, how much less to export to Europe or North America. The nation has no strategic importance to either the US or UK. Genocide in Ivory Coast will not result in one cent increase in fuel price. Will it? Ivory Coast is by far the world’s leading producer of cocoa beans, and that where your chocolate comes from. The Ivory Coast crisis may lead to some increase in the price of chocolate, but don’t we celebrate Valentine Day only once a year?

Why does the Ivory Coast deserve less than Egypt and Libya. The silence demonstrated by the World’s powers towards the Ivory Crisis is deafening, and even embarrassing.

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My HIV Problem and How I Got Cured

I have written a few of articles here in the past about some societal feelings towards our neighbors living with HIV or AIDS. My comments have centered on stereotypes and stigma associated with the disease and those who live with it. I did mention a friend of mine who contracted HIV and who, in the latter stages of his life, was completely abandoned by his own family for being sinful, perhaps.

If any of my articles appeared preachy to you, do not get mad at me yet, for I also had HIV problem. Mine was not the virus but I used to have the same troubled, prejudiced mindset about HIV and other sexually transmitted diseases, and I lived with the destructive and erosive ulcer of my thoughts for years.

As I mentioned in one of my previous articles, I heard about HIV for the first time 1986 and it was in a church, a common avenue in Ghana for the government to disseminate information to the public. The educators were a team of nurses and public health professionals from the Ministry of Health in Ghana sent by the government to tour communities and educate them about the new discovery, HIV. At that time, the information available to the instructors was scanty and only partially accurate.  There is no doubt we’ve learned quite a lot about HIV in the past 25 years. The health-care professionals came to sow the seed and it was left to the laymen of the church to continue the campaign in order to keep their flock saved from this evil. I was young, but looking back I am embarrassed by how much misinformation we were fed then and the years that followed.

Week after week and month after month, HIV was presented to us as a disease that affects sinners, and individuals who disobey the Word of God. It was nothing less than God’s retribution to deviant lifestyles and a warning for us to return to God. I imbibed this into my spirit and, for years, I also saw people living with HIV as simply paying for their trespasses. Then I began to ‘grow’ and got to know ordinary people like me who are living more decent lives than I do but who are unfortunate to be living with HIV. The result is that I lay off the childish thoughts (I Corinthians 13.11). There are many who contracted the virus through the ‘sinful’ way we know, and there are many more that got it through the many things we all do in life and take for granted. One of these people is a girl, Elizabeth from South Africa. To cut my story short, I paste here, again, a quote from Elizabeth own words:

“My mother passed away when I was five and my father when I was 10. I have been staying with my grandmother since then. I tested HIV positive in 2008 when I was 16 after being sick for a long time. I developed sores all over my body that wouldn’t heal even after taking medicine. My grandmother and I were always in and out of hospital. I missed a lot of school. At first doctors thought I had diabetes since the sores were not healing.

“After the diabetes test came back negative the doctor recommended an HIV test. At first my grandmother was against the idea but after some time she agreed. I was shocked when the result came back positive because I had never had sex. My grandmother cried too, she was very sad but the doctor explained that I may have been born HIV positive. I was very angry and blamed my parents for giving me this disease. I was immediately put on antiretroviral drugs [ARVs] and my sores healed… I feel very strong and healthy… all I want is to continue helping other people affected and infected by HIV/AIDS in my community.”

Will this change the way you see that friend, family member or neighbor with HIV? I don’t know but I hope it does. It surely changes mine.

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The Women of Benghazi

 

 

The story from the revolution in Libya and Egypt tell us one simple truth: the desire to be free is universal. Men or women, children or adults, Muslims, Christians or Jews; the desire in the soul to be free is collective.
With husbands, sons and brothers at the front, women are supporting them with meals and supplies.

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What I would Talk About if I Were a Celebrity: Spousal Rape

Valentine Day is about love, chocolate and kisses.  Mother’s Day is about extravagance, breakfast in bed and Women’s Fellowship service at church. International Women’s Day is about serious issues with dire consequences for millions of women in hundreds of countries. Marital or spousal rape is one.  The first celebration of International Women’s Day occurred on March 19, 1911, 100 years ago. Before this period, employers had their choice whether to hire women and most governments in the world, including the U.S. and Canada, prohibited women from voting. In fact, employers who decided to have anything at all to do with women relegated them to the sweatshop.

Significant progress has been made over the past hundred years but huge challenges remain for the women of today. On this anniversary, a lot has been written by more qualified experts to address some of these challenges women face. If I were a celebrity or a popular figure who people listen to, what I would love to write or talk about would be spousal rape or marital rape which occurs in several African communities and many countries.

Marital rape or spousal rape is an issue that has received very little attention internationally. I want to admit that the first time I heard the term ‘marital rape’, it sounded an oxymoron or a paradox. It was like hearing “useless treasure”, “precious garbage” or “holy dirt”. I asked myself how someone could be raped by her own partner. Isn’t that what the relationship is for?

There are millions of people, some highly educated, some not, who hold the mentality that I had. In many communities in many countries, when a woman (girl or adult) is forcibly made to have sex, it is reported as rape. No problem.  When a husband forcibly pounces on his wife and has sex with her, even when she’s least ready and least expecting it, that’s no news. She’s just the wife. In fact, journalist, don’t even cover it. Marital rape does not get any attention but it happens every single day. In many countries around the world, marital rape is either legal, or illegal but widely tolerated and accepted as a husband’s prerogative.

In a 2008-2009 Kenya Demographic and Health Survey, the report states that “at least 14 percent of married women said their current husband or partner had forced them to have sex in the past year, while another 37 percent had been subjected to sexual violence at some point in their relationship”. That is 14 out of every 100 women surveyed said their husbands had entered them forcibly in one year. And 37 women out of 100, overall! That is nearly 4 out of every 10 women! Again a World Health Organization conducted a study on violence against women in Tajikistan and Turkey. In Tajikistan they surveyed 900 women above the age of 14 and found that 47% of married women reported having been forced to have sex by their husband. In Turkey 35.6% of women had experienced marital rape sometimes and 16.3% often.  How many of these were reported? How many were covered in the evening news? And how many appeared in the local newspaper? Perhaps none. The societies accept these social behaviors and actually women who come out and report these behaviors will be stigmatized. A politician wouldn’t want to waste an ounce of their effort fighting such an irrelevant matter.

As we celebrate the international women’s day, I’ll end this by suggesting a few actions that governments, non-governmental organizations (NGOs) and communities need to take to protect the rights and dignity of women in relationships.

  • Embark on aggressive community campaigns to educate the citizenry on what sexual violence and rape in marriage implies
  • Empower the women to assert their rights and report what they perceive as rape or other forms of sexual violence
  • Enact laws to police marital or spousal rape and related violence
  • Train and provide health care professionals at the hospital who can identify what rape and other sexual violence are, who know what the law is, and how to enforce it and can show the women how to move forward. Since some of these women will eventually end up at the hospital or clinic with lacerations and other ‘fingerprints’ this will be an effective method to identify women who may have been abused.

I wish all women a Happy Women’s Day. Violence against women is violence against civilization.
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21st Century Slavery? It’s Happening as You Watch This

Slavery continues in parts of Africa today. In fact, IRIN (Integrated Regional Information Networks) of the UN Office for the Coordination of Humanitarian Affairs reports children being sold to Arab herdsmen in Chad. As part of a new identity imposed on them the herdsmen “…change their name, forbid them to speak in their native dialect, ban them from conversing with people from their own ethnic group and make them adopt Islam as their religion.

These are some of the issues TalkAfrique intends to campaign against as we assemble logistics. Please consider how you can help us to help the people affected by these evils. KAM

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Stopping Early Marriages in Africa

UNICEF helps to begin changing attitudes towards early marriage in Niger

In several communities across Africa, a young girl often does not have a say in whether and whom she will marry. It is the parents, both the man’s and the girl’s, who make the decision. In Niger, 1 out of 2 girls is married before the age of 15. But change is slowly taking place.

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Revolution and Unrest in North Africa

The current wave of revolution and uprising in North African and Middle East continues unabated. Below are the latest developments of unrests from across North Africa.

Friday developments: March 4, 2011

LIBYA

At least 15 people were killed and at least 200 wounded Friday in the Libyan city of Zawiya, a witness said. State-run Libyan TV reported that forces supporting Libyan leader Moammar Gadhafi had re-taken the city, which had been under the control of Gadhafi opponents.

Meanwhile, demonstrators and security forces clashed in the Libyan capital, Tripoli, on Friday in the latest of several confrontations that have convulsed the country and triggered an exodus of refugees. The clashes happened after weekly prayers in or close to the center of the city, two sources said, and there were indications that some force was used against demonstrators.

The eastern Libyan town of al-Brega was calm early Friday, witnesses said, a day after forces loyal to Gadhafi launched airstrikes on the oil port in an effort to reclaim it from the opposition.

Two U.S. military aircraft plan to fly to Tunisia Friday to deliver 4,000 blankets, 40 rolls of sheeting and 9,600 water cans Friday to help refugees who have fled the unrest in Libya. Nearly 180,000 people, mainly foreign workers, have fled to the neighboring nations of Tunisia and Egypt, the U.N. refugee agency reported Thursday.

Venezuelan leader Hugo Chavez has said Gadhafi is receptive to the idea of an international commission coming to the country.

Roots of unrest:

Protests in Libya started in February when demonstrators, fed up with delays, broke into a housing project the government was building and occupied it. Gadhafi’s government, which has ruled since a 1969 coup, responded with a $24 billion fund for housing and development. A month later, more demonstrations were sparked when police detained relatives of those killed in an alleged 1996 massacre at the Abu Salim prison, according to Human Rights Watch. High unemployment and demands for freedom have also fueled the protests.

EGYPT

Egypt’s new prime minister, Essam Sharaf, appeared before thousands of protesters at Cairo’s Tahrir Square on Friday, telling them he is “of the people” and would resign if he failed to meet their demands.

Sharaf, Egypt’s former transportation minister, was sworn in Friday after the resignation of Ahmed Shafik, the last prime minister appointed by Hosni Mubarak.

On Thursday, Ayman al-Zawahiri, al Qaeda’s No. 2 man, called for Egypt to establish an Islamic state in the aftermath of last month’s revolution.

Mubarak resigned February 11 after 18 days of protest against his rule. The former Egyptian ruler, who is still believed to be at his residence in Sharm el-Sheikh, will be brought to Cairo next week for questioning in a corruption case, the Prosecutor General’s office said Thursday.

Roots of unrest:

Complaints about police corruption and abuses were among the top grievances of demonstrators who forced President Hosni Mubarak from office. Demonstrators also were angry about Mubarak’s 30-year rule, a lack of free elections and economic issues, such as high food prices, low wages and high unemployment. Since Mubarak’s departure, several thousand people have protested in Cairo’s Tahrir Square to urge Egypt’s new rulers to implement promised reforms. They pressed Egypt’s Supreme Council to end an emergency law and release political prisoners, among other things. They also demanded civilian representation in government.

TUNISIA

At least three Tunisian government officials resigned Monday and Tuesday, the country’s official news agency reported, in the wake of the resignation of the prime minister on Sunday.

The minister of higher education and scientific research, Ahmad Ibrahim, and the higher education secretary, Faouzia Farida Charfi, both quit on Tuesday, Tunis Afrique Presse reported. Mohamed Nouri Jouini, the planning and international cooperation minister, resigned on Monday, the agency said.

Former Prime Minister Mohamed Ghannouchi’s resignation Sunday came a day after three people were killed during protests in the capital, Tunis.

Roots of unrest:

The revolt was triggered when an unemployed college graduate set himself ablaze after police confiscated his fruit cart, cutting off his source of income. Protesters complained about high unemployment, corruption, rising prices and political repression.

An interim government came to power after an uprising prompted autocratic President Zine El Abidine Ben Ali to leave the country on January 14. Those demonstrations sparked protests around North Africa and the Middle East.

MAURITANIA

Protesters returned to Blocat Square in the capital, Nouakchott, on Saturday, February 26, hours after police chased demonstrators from the square. One person was arrested during that melee. But young people returned by evening, promising to continue the protests over the next several days. The call to action started on Facebook, which is said to be very popular in Mauritania, sources tell CNN. Protesters are calling for job creation, economic and political changes and an end to corruption.

Roots of unrest:

In January, a man set himself on fire in front of Mauritania’s presidential palace, according to news reports — a self-immolation in the same spirit as others in Tunisia, Egypt, Algeria and elsewhere. There have been two bloodless coups since 2005 in the country, which borders Algeria and Mali, with ex-Gen. Mohamed Ould Abdel Aziz serving as president since 2009.

ALGERIA

Algeria lifted its 19-year-old state of emergency on February 22, according to the National Algerian Press Agency. The action lifts restrictions on freedom of speech and assembly imposed to combat an Islamist insurgency. Algerian President Abdelaziz Bouteflika announced last month that he would lift the emergency declaration, first imposed in 1992 and indefinitely renewed in 1993.

Roots of unrest:

Protests began in January over escalating food prices, high unemployment and housing issues. They started in Algiers but spread to other cities as more people joined and demonstrators toppled regimes in Tunisia and, later, Egypt. Analysts called Bouteflika’s announcement about lifting the state of emergency law an attempt to head off a similar revolt.

DJIBOUTI

Thousands of people have marched in protest through Djibouti. On February 18, riot police charged the crowd after the call to evening prayers, shooting canisters of tear gas at the demonstrators, according to Aly Verjee, director of the international election observation mission to Djibouti, who witnessed the event. Djibouti is home to Camp Lemonnier, the only U.S. military base on the African continent.

Roots of unrest:

Protesters have called for President Ismail Omar Guelleh — whose family has ruled the country since its independence from France in 1977 — to step down ahead of elections scheduled in April. Guelleh has held the post since 1999 and is seeking a third term. Economic stagnation is also a source of anger among the people.

SUDAN

Sudanese President Omar al-Bashir has decided not to run for another term in 2015, a senior member of Sudan’s ruling National Congress Party said. Al-Bashir has ruled since a military coup in 1989. He won another five-year term in a 2010 vote that opposition parties boycotted over complaints of fraud. He also faces an arrest warrant from the International Criminal Court on charges of genocide, war crimes and crimes against humanity in the region of Darfur.

Demonstrators have clashed with authorities on recent occasions in Sudan. Human Rights Watch has said that “authorities used excessive force during largely peaceful protests on January 30 and 31 in Khartoum and other northern cities.” Witnesses said several people were arrested, including 20 who remain missing.

Roots of unrest:

Demonstrators seek an end to National Congress Party rule and government-imposed price increases, according to Human Rights Watch. It accuses the government of being heavy-handed in its response to demonstrations, and using pipes, sticks and tear gas to disperse protesters.

MOROCCO

Protesters have taken to the streets in cities across Morocco to call for political reform. Labor unions, youth organizations and human rights groups demonstrated in at least six cities on Sunday. Police stayed away from the demonstrations, most of which were peaceful, Human Rights Watch reported.

Roots of unrest:

Protesters in Morocco are calling for political reform. Government officials say such protests are not unusual and that the protesters’ demands are on the agenda of most political parties.

Recent developments from THE UNITED NATIONS:

The U.N. refugee agency reported Tuesday that nearly 180,000 people have crossed over from Libya into Tunisia and Egypt and warned of a humanitarian catastrophe. The U.N. Security Council voted unanimously Saturday to punish Gadhafi’s regime with sanctions for violence against unarmed civilians. In an emergency session, the 15-member council also referred the strongman to the International Criminal Court for alleged crimes against humanity. Secretary-General Ban Ki-moon called for an effective solution to end the violence against anti-government protesters and a Libyan envoy tearfully asked the Security Council to step in.

Roots of unrest:

The Palestinian territories have not seen the kind of demonstrations as in many Arab countries, but the Fatah leaders of the Palestinian Authority have been under criticism since Al-Jazeera published secret papers claiming to reveal that Palestinian officials were prepared to make wide-ranging concessions in negotiations with Israel. Negotiations toward a resolution of the decades-long Israeli-Palestinian conflict have since collapsed. Palestinian protests, largely in support of Egypt and Tunisia, were generally small and poorly attended. In some cases the Hamas rulers of Gaza and the Palestinian Authority rulers of the West Bank actively tried to stifle protests. The split between Hamas and Fatah hampers internal change in the territories, although calls for political change are growing louder. Large-scale protests have failed to materialize as many Palestinians believe Israel remains their biggest problem.

 (Excerpt Unrest in the Middle East and Africa — country by country)
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