Drogba Catches Malaria

Chelsea's Didier Drogba, left
Chelsea’s Didier Drogba has been treated for malaria and will be fit to face Fulham in the Premier League on Wednesday night.
The Ivory Coast forward complained of a fever on the eve of Sunday’s match against Liverpool and only came on as a second-half substitute in a 2-0 loss.
“Obviously he lost power and training – he lost his condition,” Chelsea manager Carlo Ancelotti said Tuesday. “He’s had treatment and now he’s OK. He’ll come back immediately in the best condition.
“He suffered, obviously, because he wasn’t 100 percent but now, after treatment, he’ll be better. He had malaria. He had the tests in the last day, and they showed this kind of virus. Now he’s good.”
Ancelotti does not know where Drogba contracted malaria.
“I gave him a few days off and he went on holiday for a few days, and then he has malaria,” Ancelotti said. “But it’s over now.”
Chelsea leads the league, two points ahead of second-place Manchester United.
(The Washington Post)
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Eradicating malaria in Sub-saharan Africa, Yes We Can

Distribution of Malaria (US CDC)
Malaria is a killer. About half a million people die annually from malaria, mostly children in sub-Saharan-Africa. In fact a child dies of malaria every 30 seconds.
Even though malaria has not yet received the attention it needs on the global stage, today wealthy foundations, companies, and some governments across the world are making malaria a priority. It was hoped that this momentum would continue for a while but, as we reported here last week, a series of papers published in a respected scientific journal, the Lancet, may put pressure on the breaks.
The team of researchers cast a gloomy cloud over any hope of eradicating malaria, at least in our lifetime. I need to admit that I have not yet read all the papers but their conclusion is clear: governments, donor agencies and foundations should now focus more on minimizing the prevalence of malaria and not on eradicating malaria. It is very easy to see how this could sap away the energy of organization like Malaria no More, the Bill and Melinda Gates Foundation and other organizations toiling to see the day when there will be no more malaria.
Anyone who doubts mankind’s ability to eradicate malaria may need to be reminded that the progress on malaria eradication in the US and Canada happened over a ‘relatively short time span’. In fact, it was not until the late 1890’s that scientists even learnt that the disease is caused by a parasite and that it is a mosquito that transmits the parasite from person to person. The assumption in those days was that malaria was caused by some ‘environmental dirt’. The word malaria actually comes from the Italian “mala aria”, meaning “bad air” because it was generally believed that malaria was caused by breathing in bad or foul air and vapors emanating from swamps marshy lands and latrines.
 
It is important to remember that, 70 to 80 years ago, Americans traveling to the eastern Tennessee valleys had the same fear they now have when traveling to Togo or Ivory Coast because of malaria. The story changed with the creation of the U.S. Tennessee Valley Authority (TVA) in 1933 which established an organized malaria control program. At the time, malaria affected 30 percent of the population in the region where the TVA was incorporated. After implementing aggressive research and control operations, the disease was essentially eradicated in the TVA region by 1947.
The U.S. Centers for Disease Control (CDC) in Atlanta CDC was founded in 1946 to help control malaria. Within a few years of the campaign, malaria had been completely eradicated in the US.
The US did not win the battle over malaria overnight. Efforts to control malaria became national focus as far back as the early 20th century during the occupation American military in Cuba and the construction of the Panama Canal. It is recorded that malaria (and yellow fever) caused significant number of deaths among the workers of the canal. This triggered an aggressive program of malaria control which in 10 years had already made remarkable progress.
It is for these reasons that I have some concerns over the conclusions of the international team of researchers. Scientific possibility and budgetary recommendations perhaps should not be jammed together, especially when there is a huge regional disparity in the consequences of such recommendations.
Malaria can be defeated, albeit, not overnight. The funding available for anti-malaria campaigns, and research and development is tiny compared to the challenges. When the US announces a $10 billion annual budget for Africa it may appear too generous unless you know what we’re talking about. It is not Mali nor Zambia, but a continent of nearly 1 billion people.
We need to encourage non-governmental organizations, foundations and governments to keep on fighting. Efforts to minimize the prevalence of malaria should be encouraged but this cannot be an open-ended laissez faire attitude with no responsibility. There should be an aggressive program to eradicate the disease as it was done in the US and Canada.
Yes We Can
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New scientific finding on mosquitoes is not good news on the malaria front

Mosquito sp. Anopheles gambiae is responsible for malaria

The research team of researchers from the University Of Notre Dame, the J.C. Venter Institute, Washington University and the Broad Institute are reporting that two strains of mosquitoes responsible for malaria in Africa are evolving at an unexpected rate into genetically distinct species. This is not good news as it will further complicate the tedious fight against malaria by creating a situation where strategies and medicines developed against malaria may not be effective against both strains

The studies were reported in the magazine Science. The two issues (Science 22 October 2010:Vol. 330. no. 6003, pp. 512 – 514; Science 4 October 2002:Vol. 298. no. 5591, pp. 115 – 117) suggest that the evolution process is occurring faster than previously thought, and point to already substantial differences in the two strains. The two species already able to exploit different habitats.

Malaria kills one child every 30 seconds worldwide, according to World Health Organization. The incidence could be higher in sub-Saharan African.

The work focused on the Anopheles gambiae, the mosquito that is the most transmitter of malaria in sub-Saharan Africa. The study describes the two strains as “M” and “S” strains of the “Anopheles gambiae mosquito

What they found was that the mosquitoes are diverging into two different incipient species, which are called M and S forms. Physically, the two forms are cannot be distinguished, they are and able to interbreed, but their DNAs are diverging into different directions. Their behaviors are different under different conditions.

The ‘M’ form is usually found in around permanent bodies of water and spends most of its life in water environment. This means that it can thrive in dry areas that are normally not good habitats for malaria transmitting mosquitoes.

The S form is used to small, short-lived water bodies and breeds well during the rainy season. It is clear how these ‘tricks’ by the mosquito could undermine current efforts to combat the disease.

Work is ongoing to sequence the genome of the two forms of mosquitoes which could help us to decipher why they are different and how to devise ways to combat them more effectively.

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Africa Command: Opportunity for Engagement or the Militarization of U.S.-Africa Relations? Dr Wafula Okumu

 Background

Until recently, Africa has not been strategically attractive to the U.S.  This is partly because U.S. interests in Africa had not been clearly defined and it had no bureaucratic structure to manage those almost nonexistent interests. For a long time, the strategic thinking has been that the U.S. has “no compelling interests in Africa” and “do not want anybody else to have any, either.” However, whenever a non-Western nation or idea made its way into Africa, the U.S. got very nervous. This is what happened from the 1960-1990, when the Soviet Union tried to spread its communist ideology to Africa. Today, many think the U.S. is very nervous of Chinese economic penetration into Africa. America’s concern is that the Chinese are trying to control the continent’s natural resources and gain influence over it. The U.S. is also worried that radical Islamism is a dangerous idea that could germinate in poorly and badly governed states of Africa. Africom is being sold as an answer to these threats. Until the enunciation of Africom, the continent had been haphazardly divided into three U.S. commands—European, Central and Pacific.  In order to understand this state of affairs we need first to understand the basis of U.S. foreign policy towards Africa.

Basis for Understanding U.S. foreign policy towards Africa

U.S. foreign policy towards Africa has been variously referred to as either “benign neglect” or “manifest destiny.” In other words, these postures have defined or driven U.S. relations with Africa. Despite changes of U.S. administrations since 1960, when most African countries started gaining independence, the substance has always remained the same. Only the styles of various administrations have changed. As we shall see later, when given a choice between supporting the liberation struggles of the African people or bolstering its NATO allies, the U.S. easily chose the latter. On the other hand, it has sent Peace Corps volunteers to remote villages to assist in improving agricultural production while at the same time erecting trade barriers against products of these local farmers. It is this principle of “manifest destiny” that seems to be embodied in Africom’s objectives and stated mission.

Africom’s Stated mission

Prevent conflict by promoting stability regionally and eventually ‘prevail over extremism’ by never letting its seeds germinate in Africa.

Address underdevelopment and poverty, which are making Africa a fertile ground for breeding terrorists.

 “…view the people, the nations and the continent of Africa from the same perspective that they view themselves.”

Build the capacity of African nations through training and equipping African militaries, conducting training and medical missions.

Undertake any necessary military action in Africa, despite its non-kinetic nature such as humanitarian assistance and disaster relief.

Why the U.S. really wants to set up Africom

Despite the above stated objectives, there are many reasons why the U.S. wants to set up Africom. First, the U.S. has become increasingly dependent on Africa for its oil needs. Africa is currently the largest supplier of U.S. crude oil, with Nigeria being the fifth largest source. Instability, such as that in the Niger Delta, could significantly reduce this supply. The U.S. National Intelligence Council has projected that African imports will account for 25% of total U.S. imports by 2015. This oil will primarily come from Angola, Ghana, Equatorial Guinea, Gabon, and Nigeria. Nigeria, Africa’s largest oil producer, has now overtaken Saudi Arabia as the third largest oil exporter to the U.S.  The importance of the African oil source can be gleaned from the fact that in 2006, the U.S. imported 22% of its crude oil from Africa compared to 15% in 2004. President Bush appeared to have African oil supplies in mind during his 2006 State of the Union Address, when he announced his intention “to replace more than 75% of (U.S.) oil imports from the Middle East by 2025.” Continuing unrest in the Middle East has increased the urgency for the U.S. to build a security alliance with Africa in order to achieve this goal.

Second, Africa is an unstable region with badly governed states that can only manage their affairs, particularly security-related, with outside assistance. Since September 11, 2001, U.S. foreign policy has heavily focused on preventing and combating global terrorist threats. The events of 9/11 changed the way the U.S. views and relates to the rest of the world. Likewise, the foreign policies of Western powers have increasingly been militarised to secure and defend Western interests. Terrorism has been identified as one of the biggest threats to these interests. Africom is expected to stop terrorists being bred in Africa’s weak, failing and failed states from attacking these interests.

It is widely held in the West that failing and failed states in Africa create opportunities for terrorists to exploit. Among the targets of these terrorists are Western interests such as oil sources and supply routes. Improvement of African security would inevitably promote U.S. national interests by making it less likely that the continent could be a source of terrorism against the United States.

Third, one of the critical challenges facing Africa and the UN is training, equipping and sustaining troops in peace missions. African armies need training in peacekeeping. It is proposed that through Africom, African troops will be trained and aided to keep the peace in African conflict zones. This should come in handy when it is considered that all African Union-led peacekeeping operations deployed so far have encountered monumental problem

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Comedy Versus Malaria

Mosquito vs Comedy
Mosquito vs Comedy

A non-profit Malaria No More is using humor to keep malaria in the news. The actors include a broad range of stars including Ed Helms, John Mayer, Elizabeth Banks, BJ Novak and Nick Kroll. The organization want to use humor to raise awareness for malaria in Africa. A child in Africa dies from malaria every 30 seconds!

Comedians take on malaria

The actors have set up Malaria No More fan page on Facebook. I encourage you to join them. You can get a good laugh and help save a life.

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A Breakthrough in Malaria Research

Scientists from Scotland have reported a major breakthrough  in fight against malaria.

The team from Edinburgh University in collaboration with  a team in Portugal  have discovered a gene that offers the drug resistance trait to the parasite. Drug-resistant plasmodium falciparum parasites are a major hindrance in the battle against the deadly disease. Chloroquine, the most commonly prescribed medicine against malaria has lost its effectiveness due to the proliferation of chloroquine resistant parasites.

Scientists think this is a  major development in malaria research. Malarial kills one to three million people annually, mostly children. These findings may pave a way for a new class of anti-malarials.

The study has been published in Biomedical Central (Sept 2010)

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