Celebrities Who Took Gaddafi’s Money

He may have been feared and loathed by some of his own citizens and leaders from the developed world, but there was a group of people who loved Col Muammar Gaddafi and his money.

Gaddafi, who was murdered on Thursday in his birth town of Sirte, lived large and when he wanted to be entertained, he did not turn on the radio or his TV, he got some of the biggest names in the world of music to do the job.

Beyonce, 50 Cent, Enrique Iglesias, Lionel Richie, Mariah Carey, Nelly Furtado, Timbaland and Usher are some of the prominent names who made millions of dollars from entertaining Gaddafi and his family.

Other celebrities like Jay-Z, Jon Bon Jovi, Bob Johnson and Russell Simmons are also said to have attended the private performances.

A memo released by the whistle-blowing site Wikileaks described lavish parties thrown by one of Gaddafi’s sons on the Caribbean island of Saint Bart’s where singers Beyonce and Usher were paid large sums to perform at the gathering.

As expected, these celebrities don’t come cheap and Gaddafi didn’t mind paying for their services.

Beyonce received $2m (Sh200 million current rate) to perform for the Gaddafi family in 2009 New Year’s bash reportedly for Gaddafi’s fourth son Muastassim, who was also killed with his father on Thursday.

She revealed in March that she was donating the money to to the Haitian earthquake relief fund.

“All monies paid to Beyoncé for her performance at a private party at Nikki Beach St Barts on New Year’s Eve 2009, including the commissions paid to her booking agency, were donated to the earthquake relief efforts for Haiti over a year ago,” the “Put a ring on it” singer’s publicist said in a statement to The Huffington Post.

Mariah Carey followed, saying she felt “horrible and embarrassed” for being paid $1 million (Sh100 million) to sing four songs at the New Year party in 2008.

Held accountable

“Going forward, this is a lesson for all artists to learn from,” said Carey. “We need to be more aware and take more responsibility regardless of who books our shows. Ultimately we as artists are to be held accountable.”

Singer Usher, who was paid not to perform but to do the midnight countdown at the same New Years party, said he was “sincerely troubled” by the origin of the money and would give his earnings “to various human rights organisations.”

Nelly Furtado, who performed for the Gaddafis for 45 minutes at an Italian hotel in 2007 received $1 million (Sh100 million), announced she would also donate the money to charity.

Rapper 50 Cent was also forced to donate the money he made after performing at a private gig for Mutassim Gaddafi, in Venice in 2005.

A statement from a representative for 50 Cent said: “In light of the ongoing events in Libya, 50 Cent will be making a donation to Unicef, which is providing vital relief supplies to meet the needs of women and children at risk during this crisis.”

Celebrities and dictators have a weird connection and have always been linked together. The dictators want to be entertained and the celebrities want their dollars.

Last week, Hollywood actors Hilary Swank, Jean-Claude van Damme and soul singer Seal were in trouble after they entertained Chechen President Ramzan Kadyrov at his multimillion-dollar 35th birthday party in early October. Chechen is said to have an “atrocious human-rights record”.

Kadyrov is accused of being one of the world’s most notorious human rights violators, with an alleged history of arson, abductions and torture against people who aren’t hot celebrities.

“I deeply regret attending this event, which has thrown into question my long and deeply-held commitment to the protection of human rights,” Swank said in the statement.

Michael Jackson fled to Bahrain after he was acquitted of molesting young boys and was hosted by Bahrain’s Prince Abdullah al-Khalifa.

British supermodel Naomi Campbell is alleged to have received a huge “blood diamond” from ousted Liberian dictator Charles Taylor. She denied the allegations before the ICC.

Mobutu Sese Seko

One of Africa’s most brutal dictators, Mobutu Sese Seko hosted the famous “Rumble in the Jungle” fight and a concert as part of the “authenticity campaign” for the new country, Zaire.

The concert, dubbed Zaire 74, was held six weeks before the fight was attended by legends James Brown, Celia Cruz and the Fania All-Stars, B.B. King, Miriam Makeba, the Spinners, and Bill Withers.

It was originally intended to be the same weekend as the fight, but Foreman suffered an injury that pushed the concert back six weeks.

Mobutu paid $5 million (Sh500 million) each to Muhammad Ali and George Foreman to bring their famous boxing feud to Zaire’s capital.

Daily Nation

Share

Republican Rick Perry Doesn’t Have a ‘Definitive Answer’ Whether Barack Obama is a US Citizen

Republican presidential candidate Rick Perry walked a fine line when presented with questions about President Barack Obama’s birth certificate — which was released by the White House earlier this year — in a new interview with Parade magazine published online.

When asked if he believes the president was born in the United States, the Texas governor said, “I have no reason to think otherwise.” Pressed on the nature of his answer, Perry added, “Well, I don’t have a definitive answer, because he’s never seen my birth certificate.”

Here’s an excerpt of the subsequent exchange that went down on the birth certificate issue:

But you’ve seen his. I don’t know. Have I?

You don’t believe what’s been released?
I don’t know. I had dinner with Donald Trump the other night.

And?
That came up.

Perry said that Trump doesn’t believe the document released by the White House is “real.” Asked if he agrees with the sentiment, the Lone Star State Republican said, “I don’t have any idea. It doesn’t matter. He’s the president of the United States. He’s elected. It’s a distractive issue.”

Leading up to the release of Obama’s “long form” birth certificate in April, Trump captured headlines and sparked controversy with his persistence in raising doubt over the president’s birthplace.

Trump went as far to release his own official birth certificate. Upon the release of the president’s birth certificate, Trump said that he was very “proud” of himself.

Share

Exercise May Not Limit Weight Gain by Pregnant Moms

Exercise and weight gain unrelated

Exercising during pregnancy was safe for both moms and babies in a new study of heavy women in Brazil, but fitness classes and at-home exercises didn’t keep moms-to-be from gaining too much weight.

The finding is “not surprising,” according to Dr. Patrick Catalano, a maternal-fetal medicine researcher from Case Western Reserve University School of Medicine in Cleveland.

“Lots of studies have not shown any benefits relative to weight gain in pregnancy using either diet or exercise,” said Catalano, who didn’t participate in the new research.

The U.S.-based Institute of Medicine recommends that overweight women should gain between 15 and 25 pounds during pregnancy, and obese women 11 to 20 — less than the amount recommended for normal-weight women.

Being overweight or obese while pregnant, or gaining too much weight during pregnancy, increases the chance of having a large baby and needing a Cesarean section. It also ups the risk that babies will have birth defects or grow up to be obese, researchers said.

Plus, women who gain a lot of weight during pregnancy tend to keep in on afterwards, Catalano told Reuters Health.

He said that starting an exercise or diet program mid-way through pregnancy probably isn’t as useful as intervening very early in pregnancy — or better yet, before.

‘MODERATE EXERCISE IS VERY GOOD’

In the current study, researchers led by Simony Nascimento from UNICAMP Medical School in Campinas recruited 82 heavy women who were already between three and five and a half months into their pregnancies.

They split those women into two groups. Half went to weekly exercise classes and got counseled on nutrition, weight gain and home exercises or walking they could do daily. The other women received standard prenatal care advice, but no extra information on exercise.

Regardless of whether they were assigned to do group and at-home exercise, about half of the women gained more weight than recommended upper limits.

On average, obese women gained 23 to 24 pounds in both groups. Overweight women gained an average of 22 pounds when they exercised and 36 when they didn’t, but the researchers caution that those findings were based on a small group of only 14 women.

The majority of all babies were born by c-section, but there was no difference in their health at birth based on whether or not moms exercised, Nascimento and colleagues report in BJOG: An International Journal of Obstetrics and Gynecology.

Catalano said the findings don’t take away from the fact that, “moderate exercise is very good, no question about it.” But he said that the farther women get into pregnancy, the harder it is for them to stick to an exercise program. That’s why starting with exercising and diet improvement early is so important.

One of the problems is that historically, women have been given the wrong message about eating and physical activity in pregnancy, said Dr. Raul Artal, head of obstetrics, gynecology and women’s health at Saint Louis University School of Medicine.

“Pregnancy is not a state of confinement and indulgence. It’s an ideal time for behavioral modification for the benefit of both mother and the baby,” Artal, who wasn’t involved in the new research, told Reuters Health.

He considers pregnancy an opportunity to address unhealthy behaviors in patients. “In general women are more prone to adopt healthy lifestyles in pregnancy because of the concern for the unborn child.”

Nascimento’s team also pointed out that women typically have more contact with health providers when they’re pregnant.

But, Artal added, “The sad thing is that as a society we have become more sedentary and more overweight and obese. This is not confined to pregnant women.”

In an email to Reuters Health, the researchers recommended 30 minutes of moderate exercise each day for overweight and obese pregnant women, along with stretching and nutrition counseling.

Source: Reuters Health

Share

Reaching Out to ‘Emerging Donors’ for Africa

Analysis

Dakar — Guyana, Thailand, Botswana, South Africa, Poland and Sudan share something in common: they all committed to the Horn of Africa drought appeal.

Higher up the scale, with multi-million dollar pledges, were China (US$63 million); Saudi Arabia ($60 million); Brazil ($32 million); United Arab Emirates ($17 million) and Qatar ($5.6 million).

Non-DAC donors – countries that are not members of the Organisation for Economic Co-operation and Development’s Development Assistance Committee – reported $622 million worth of humanitarian assistance in 2010 and contributed 6 percent of total reported humanitarian aid between 2000 and 2008, according to the UN Office for the Coordination of Humanitarian Affairs (OCHA) Financial Tracking Service.

When it comes to all types of foreign assistance, non-DAC donors are collectively estimated to have given $60 billion in 2010, according to aid watchdog Development Initiatives; and the UN estimates non-western donors provided almost 10 percent of overall aid in 2008. South-south trade meanwhile, accounted for more than a quarter of global trade in 2008.

Growing influence

Though many non-DAC donors’ aid pots are still relatively small (India reported just $36.5 million in humanitarian aid in 2010), amounts grow annually (in 2000 it gave $200,000); their economic clout is growing (India is tipped to be the third-largest global economy in 2020), and many are shunning the stigma of “recipient-only-status”, says Shoko Arakaki, chief of funding coordination at OCHA.

But the power of these new donors extends beyond money. As well as being a significant donor to Haiti in 2010, Brazil wielded influence by leading the UN Stabilization Mission for Haiti (MINUSTAH). The government plays an active role in global disaster preparedness, such as the International Strategy for Disaster Reduction and Global Facility for Disaster Reduction and Recovery (GRDRR), according to Germany-based Global Public Policy Institute (GPPi).

The influence of these donors is likely to grow further, says Claudia Meier, public research associate at GPPi, and could reshape coordination and accountability bodies, such as the DAC, which have to date remained relatively “closed”. Of the emerging donors only South Korea has joined DAC. It has also joined the Good Humanitarian Donorship Initiative alongside Poland, Brazil, Estonia and Lithuania – the GHD is reaching out to Turkey, Croatia, United Arab Emirates and Singapore to join.

Some emerging donors shun membership of these structures as they have not been part of their establishment, said Meier, who wrote Humanitarian Assistance: Truly Universal?, which analyzes entry points for collaboration with non-western humanitarian donors.

Brazil cited this as a reason for not joining the DAC. Many prefer regional coordination bodies, says GPPi, such as the Association of Southeast Asian nations (ASEAN), the Organisation of the Islamic Conference or the League of Arab States, which are “taking a more active role in [humanitarian] coordination”.

As Karin Christiansen, head of Publish What You Fund (PWYF), told IRIN: “Both the system and the donors need to change… Emerging donors might drive this reform… Ultimately, the more people in the tent, the language will have to change.”

Other likely changes are the growing influence of consortia and pooled funds, into which donors – both traditional and not – are putting increasingly large amounts, says deputy funding director at Oxfam, Suzi Faye.

Relief organizations from emerging economies are also likely to develop more of an international humanitarian role, said Meier. “Maybe an Indian NGO, the Chinese Red Cross, the Red Crescents of the Gulf States [will emerge]… they are not fully there yet, but there are lots of signs of their professionalization,” she said.

Opportunities

Opportunities arise with donor diversification, said Kerry Smith, researcher with aid watchdog Development Initiatives. Emerging donors often tend to be recipients and providers of aid, and thus have a better understanding of the needs and constraints facing developing countries in emergency response. India has sophisticated disaster management systems after decades of disaster response, and has helped shape those of Pakistan and Afghanistan – two of its largest aid recipients.

These donors often tend to stress a more equal, solidarity-based relationship, rather than the traditional top-down donor-recipient dynamic, said Smith. As Brazil said: “[The Brazilian government believes that] development cooperation is not limited to the interaction between donors and recipients [and] understand[s] it as an exchange between peers, with mutual benefits and responsibilities.”

Many non-western donors do not distinguish short-term humanitarian aid from longer-term “development aid” – perhaps because they know the distinction to be blurred – which could help plug the gaps in the usually under-funded relief-to-development continuum.

Further, tapping into aid from “new” sources can in some circumstances increase aid agencies’ access to those in need – most aid workers agree that humanitarian space has shrunk over the past two decades.

For example, India is one of the few humanitarian donors in Afghanistan that is not involved in the conflict; in Myanmar, many western-backed NGOs found it hard to respond to Cyclone Nargis but those working with ASEAN donors were able to intervene more quickly, partly because of its long-term relationship with the Burmese authorities.

Non-western donors may also take a more sensitive approach to respecting a country’s sovereignty, say analysts. India puts sovereignty at the heart of its humanitarian response policy, having refused an onslaught of aid after the 2004 tsunami. In future, aid agencies will need to pay greater attention to “non-intrusive support”, wrote Randolph Kent of the humanitarian futures project, in Death of Hegemony.

“When western agencies rolled up after the Sichuan earthquake in China, the Chinese told them flatly they were not needed. Generally, greater sensitivity to regional culture, gaining real knowledge of what is wanted by governments and communities in disaster-prone regions and building contacts in those regions well before another humanitarian disaster, is the way in which the west can continue to play an international humanitarian role – rather than the presumption that it is wanted and needed.”

Reaching out

As the donor picture shifts, aid agencies are starting to build new relationships, but too slowly, said Meier. “Not enough dialogue is going on yet.”

One exception at a policy level is the UN-based humanitarian dialogue platform, chaired by Sweden and Brazil, which tries to “bridge the artificial donor-affected population gap and to discuss humanitarian assistance among all states on a consistent basis”, said Meier.

Some UN agencies have also been fairly active at forging relationships with new donors, say analysts, including World Food Programme, the UN Children’s Fund, and the UN Relief and Works Agency (UNRWA), which respectively received 2.5 percent, 1.7 percent and 3.6 percent of their humanitarian funding from non-DAC donors in 2008, after significant reach-out – particularly to Gulf donors.

OCHA, which coordinates the Emergency Response Fund, Country Humanitarian Fund and the Central Emergency Response Fund, has made a big effort to reach out to new donors, said Arakaki – and the results are starting to show.

The ERF and CHF have increased their donor bases in the past 15 years, with 40 donors, including Brazil, UAE and Mexico, Nigeria and Gabon among the top 10 contributors to the Haiti emergency Response Fund, she said.

The CERF is even more diverse, with 140 donors in 2010. Unique to the fund is that 40 of its donors are also recipients. “The more new members that come on board, the more of an example it sets… Donors also realized today’s donor can be tomorrow’s victim,” said Arakaki.

The draw of such pooled funds to some emerging donors is ease: they can write a cheque and OCHA does the rest. “Many of them want to identify the simplest mechanism to give money as quickly as possible,” said Arakaki.

This is particularly true for governments that do not have the legal set-up to administer and track foreign funding. The law in Poland, for instance, means it can take up to three months to disburse money to a national or international NGO; thus the government finds it much easier to give to pooled funds or UN agencies and the International Federation of the Red Cross, according to Development Initiatives’ Smith.

The amounts are still small, however: 90 percent of CERF funding in 2010 still came from the same “traditional” 10-12 donors.

NGOs catching up

Whether it is murky entry points for dialogue, emerging donors’ penchant for pooled funds, or a host of other reasons, NGOs appear to be behind UN agencies in reaching out to new donors. Most of the big international NGOs are building relationships: World Vision for instance, fund-raises in Thailand, the Philippines, India, Malaysia, Mexico, Brazil, Colombia and Chile through its country offices, according to spokesman Christopher Weeks, and the South Korea and Taiwan offices now donate funds, rather than receive funds, he said. But the numbers remain small.

Gulf donors contributed just $1.5 million to Oxfam’s $473 million annual budget, according to Faye. But building relationships with these donors is still important. “Rather than just going after money, we are trying to build real partnerships, as well as seeing how Oxfam can influence them on a policy level.”

GPPi acknowledges the challenges involved in finding “entry points for dialogue”: many emerging donors – such as South Africa – do not have separate development ministries to administer aid; Brazil has a fragmented aid system, with no legal framework to regulate, monitor or evaluate aid, according to the Overseas Development Institute, while the aid motivations of India remain largely unknown.

There is “great variance” in donor transparency, according to PWYF’s Christiansen: Estonia is “extremely transparent” at one end of the scale, while China is “not as murky as everyone thinks”, she said. PWYF will be releasing a report on emerging donor transparency in November. For those donors still honing their humanitarian and development financing systems: “There are benefits to setting up good transparent systems from the beginning… If you have to retrofit, then it is much harder,” Christiansen says.

For relationships to work, emerging donors need more respect, a representative from one emerging donor’s foreign aid ministry told IRIN in Dakar: many of them have been giving aid for decades without being noticed, he said. Meier added: “They all of a sudden have been discovered as cash cows, while still not getting a say in international governance.”

The DAC still does not include China, Russia, Saudi Arabia or Brazil, and no meeting ground exists for all donors to discuss humanitarian assistance other than the annual UN General Assembly and the Economic and Social Council (ECOSOC). “This reinforces the idea of aid being part of the western agenda,” said Antonio Donini, researcher at Tufts University’s Feinstein institute.

An NGO, One.org, has called on emerging donors to join existing coordination structures. But Christiansen says these structures themselves need to change to be more welcoming to new members. She hopes forging a mutually respectful dialogue between aid agencies, new and established donors, will be on the agenda at the aid effectiveness conference in Busan, South Korea in November.

“Things may get messier before they become clearer, but it is already incredibly messy – we need a bit less hubris, and a bit more action,” she said.

This report does not necessarily reflect the views of the United Nations

Copyright © 2011 UN Integrated Regional Information Networks.

Share

The Rise of the ‘New’ Donors for Africa

Dakar — “It’s taken the world a while to notice they exist – and now we’re obsessed with them,” is how Karin Christiansen, head of Publish What You Fund, characterizes the west’s relationship with what people call “new”, “emerging” or “non-traditional” donors.

Many are not new at all – India, Brazil and China have been giving aid for decades – but what is new is that a group of non-western donors is giving more humanitarian and development aid year on year, and reporting it more consistently to official trackers, such as the UN’s Financial Tracking System (127 donors reported aid in 2010).

As they “emerge”, the traditional hegemony held by western donors over how and where aid is dispersed is starting to be dismantled.

“A hegemony or sense of tradition has developed over decades in the western humanitarian movement, that it should spearhead response to disasters because it has special experience and ability,” says Randolph Kent head of the Humanitarian Futures programme at King’s College, London.

“But increasingly we are seeing more and more humanitarian players from the east responding to disasters – India, China, Vietnam and Bangladesh for example – are more than capable of responding and managing crises in their own countries.”

These donors do not necessarily want to join the Organization for Economic Co-operation and Development (OECD) Development Aid Committee – they are forming their own localized coordination groups instead.

Brazil and Spain signed an agreement in 2011 to jointly implement aid projects; Russia recently partnered with Venezuela on Haiti earthquake response; Brazil, India and South Africa set up a Poverty and Hunger Alleviation Fund in 2011.

Many are the same governments that have argued for years for a less top-down, more partnership-oriented approach when receiving aid. India, after all, was both the eighth-largest receiver of official development assistance in 2008 and is expected to be the third-largest economy by 2020.

Some governments are growing increasingly frustrated with the western domination of inter-governmental bodies such as the World Bank and International Monetary Fund. Brazil, Russia, India and China issued a communiqué in April 2011 stating: “The governing structure of the international financial institutions should reflect the changes in the world economy, increasing the voice and representation of emerging economies and developing countries.”

Western powers are not showing themselves keen to shift too much, yet. But in due course, all donors will be forced to shift at least a little, say analysts. In light of these changes, IRIN discusses just how transparent is China’s aid programme; analyzes the rising influence of Muslim and Arab donors and aid agencies; and asks analysts whether aid agencies are preparing sufficiently for the future by reaching out to new donors such as Brazil and India.

Copyright © 2011 UN Integrated Regional Information Networks.

Share

Link Between Mobile Phones and Brain Cancer Rejected

By Nick Triggle Health correspondent, BBC News

Further research has been published suggesting there is no link between mobile phones and brain cancer.

The risk mobiles present has been much debated over the past 20 years as use of the phones has soared.

The latest study led by the Institute of Cancer Epidemiology in Denmark looked at more than 350,000 people with mobile phones over an 18-year period.

Researchers concluded users were at no greater risk than anyone else of developing brain cancer.

The findings, published on the British Medical Journal website, come after a series of studies have come to similar conclusions.

‘Reassuring’

But there has also been some research casting doubt on mobile phone safety, prompting the World Health Organization to warn that they could still be carcinogenic.

In doing so, the WHO put mobile phones in the same category as coffee, meaning a link could not be ruled out but could not be proved either.

The Department of Health continue to advise that anyone under the age of 16 should use mobile phones only for essential purposes and keep all calls short.

Continue reading the main story

“Start Quote

These results are the strongest evidence yet that using a mobile phone does not seem to increase the risk of cancers of the brain or central nervous system in adults”

Hazel Nunn Cancer Research UK

The Danish study, which built on previous research that has already been published by carrying out a longer follow-up, found there was no significant difference in rates of brain or central nervous system cancers among those who had mobiles and those that did not.

Of the 358,403 mobile phone owners looked at, 356 gliomas (a type of brain cancer) and 846 cancers of the central nervous system were seen – both in line with incidence rates among those who did not own a mobile.

Even among those who had had mobiles the longest – 13 years or more – the risk was no higher, the researchers concluded.

But they still said mobile phone use warranted continued follow up to ensure cancers were not developing over the longer term, and to see what the effect was in children.

Hazel Nunn, head of evidence and health information at Cancer Research UK, said: “These results are the strongest evidence yet that using a mobile phone does not seem to increase the risk of cancers of the brain or central nervous system in adults.”

Prof Anders Ahlbom, from Sweden’s Karolinska Institute, praised the way the study was conducted, adding the findings were “reassuring”.

Prof David Spiegelhalter, an expert specialising in the understanding of risk who is based at the University of Cambridge, said: “The mobile phone records only go up to 1995 and so the comparison is mainly between early and late adopters, but the lack of any effect on brain tumours is still very important evidence.”

And Prof Malcolm Sperrin, director of medical physics at Royal Berkshire Hospital, said: “The findings clearly reveal that there is no additional overall risk of developing a cancer in the brain although there does seem to be some minor, and not statistically significant, variations in the type of cancer.”

But the researchers themselves do accept there were some limitations to the study, including the exclusion of “corporate subscriptions”, thereby excluding people who used their phones for business purposes, who could be among the heaviest users

Share

Libya Dictator Muammar Gaddafi Killed

Libya’s ex-leader Col Muammar Gaddafi has been killed after an assault on his home town of Sirte, officials from the transitional authorities have said.

Information Minister Mahmoud Shammam said fighters had told him they had seen Col Gaddafi’s body, and other officials also said he was dead.

The claims have not yet been independently verified, and other reports said he was captured alive.

The colonel was toppled in August after 42 years in power.

The International Criminal Court has been seeking his arrest.

Golden gun

Nato, which has been running a bombing campaign in Libya for months, said it had carried out an air strike earlier on Thursday that hit two pro-Gaddafi vehicles near Sirte.

It was unclear whether the strikes were connected with the reports of Col Gaddafi’s death.

Mr Shammam said NTC leaders would officially confirm Col Gaddafi’s death later.

“He was killed in an attack by the fighters. There is footage of that,” he said.

Grainy video footage has been circulating among NTC fighters appearing to show Col Gaddafi’s corpse.

The video shows a large number of NTC fighters yelling in chaotic scenes around a khaki-clad body, which has blood oozing from the face and neck.

Driving into the centre of Tripoli, there are throngs of people out on the streets – men, women and children – many hugging each other and chanting. Gunshots can be heard firing into the air – despite a religious edict banning the practice. Car horns are blaring and many vehicles have their emergency lights blinking.

At some checkpoints, security officials are handing out what have been dubbed “revolutionary mints” and biscuits.

All the flags are out. People are genuinely convinced this is the end of Col Gaddafi. They felt that even in hiding he posed a threat to the revolution – but for them this news means the authorities can now start to rebuild the country.

Another video broadcast by al-Jazeera TV showed a body being dragged through the streets which the channel said was that of Col Gaddafi.

NTC official Abdel Hafez Ghoga told AFP: “We announce to the world that Gaddafi has been killed at the hands of the revolution.

“It is an historic moment. It is the end of tyranny and dictatorship. Gaddafi has met his fate.”

An NTC fighter told the BBC he found Col Gaddafi hiding in a hole in Sirte, and the former leader begged him not to shoot.

The fighter showed reporters a golden pistol he said he had taken from Col Gaddafi.

Arabic TV channels showed images of troops surrounding two large drainage pipes where the reporters said Col Gaddafi was found.

NTC supporters gathered in towns and cities to celebrate the reports of the colonel’s death.

Groups of young men fired guns in the air, and drivers honked horns in celebration.

His apparent death came after weeks of fierce fighting for Sirte, one of the last remaining pockets of resistance

Share

Malaria Vaccine: Now A Possibility

GlaxoSmithKline research head Moncef Slaoui explains how change of focus to cellular immunity was key to breakthrough

Moncef Slaoui was on holiday with his family when he heard the results of the first small trial, involving African infants, of the malaria vaccine he helped invent. It was a day he would never forget.

“It was 9 August 2004,” he said. “I’m on vacation with my kids, driving between Chicago and Indianapolis and my phone rings and it’s the team calling from Mozambique. I had to stop for at least an hour. I couldn’t drive any more. That was a big, big moment.”

The vaccine had been classed as around 55-60% effective. It was the first sign that Slaoui, now chair of R&D at GlaxoSmithKline, and his colleagues, were going to be successful in cutting the terrible toll of malaria in Africa. Halving the 200m cases a year would save lives and prevent a huge amount of harm.

It had been a long haul. Slaoui had joined the Belgian lab of what was to become GlaxoSmithKline 23 years ago with a background in immunology. “I brought a fresh perspective in what was then modern immunology,” he said. Some of his new colleagues had started work on a malaria vaccine but “it was more or less stalled conceptually”.

No one then had managed to make a vaccine against a parasite infection. Many in the scientific community thought it impossible. “We heard that a lot. There were many controversial discussions on whether we would be able to achieve success,” said Slaoui.

But his ideas drove the effort in a new and successful direction.

Scientists had been attempting to kill off the parasites injected by malarial mosquitoes as soon as they entered the bloodstream. But any vaccine attempting that has only minutes to work because the parasites quickly go to the liver, where the next stage of their life cycle occurs. After five days there is a burst of new parasites in to the blood cells and that is when the child falls ill.

Slaoui suggested using cellular immunity. “Rather than using antibodies that can kill bacteria or a parasite, we used T-cells that recognise [a] cell is not normal because it is infected by a parasite. It opened the opportunity to find the parasite where it [hid] in the liver and kill it there.”

It was easy to say, but hard to do. They needed to find the right adjuvant, a substance that would stimulate the immune system’s T-cells to mount a response against the malaria parasites.

It was in 1996, eight years after Slaoui joined the vaccine effort, that they became sure they were on the right track – during experiments in conjunction with the Walter Reed army medical centre in Washington DC.

Slaoui said: “It was the first demonstration of the proof of concept that we were able to make a vaccine that killed the parasite in the blood and also in the liver.”

The approach used would later be employed in GSK’s pandemic flu and cervical cancer vaccines, which would make money. Slaoui said GSK would not have dropped the malaria vaccine programme, which was solely for the benefit of people too poor to pay, but that the proftable spin-offs undoubtedly helped.

He said: “GSK Biologicals’ leadership was always totally committed to continue the work on the malaria vaccine for two equally good reasons. The malaria vaccine was a great vehicle to advance our platform of adjuvants for many other vaccines, [ones] that were more able to give us a return. But secondly there was truly a commitment to public health in general and our responsibility to society to make vaccines for those who would most benefit, even when they could not afford it.”

This was a stronger motivation in the vaccine community than in the pharmaceutical industry. He added: “Vaccines are associated with public health and the developing world and babies that you save from major infections, and therefore the idealistic motivation is very strong.”

It remained the case, he said. “Yesterday in Seattle [when the results were published] I was with some of the first core-team members – we all started together. It was very emotional.

Share